Murky vs Varian
Varian is the reverse of most Heroes in that Varian is easy to lane against in the beginning. Varian's wave clear is not great and he does not have his talents yet. When Varian charges Murky you should bubble out of the slow and retreat.
Once Murky gets Fish Tank it is useless against Varian. That is because his overpower strikes are ability based. Rejuventing Bubble would be better for Varian.