Murky vs Valla
Murky should avoid laning against Valla. Valla can kill Murky and his puffer fish easily. Murky can kamikaze Valla and force her to retreat for health. Another alternative is for Murky to backup to the gate and kill minions there.
Once Murky gets Fish Tank Valla becomes much more manageable. Murky still needs to bubble for Valla homing arrow. If Vallas takes the multishot talent with gernades the Murky is toast. Fortunately that is considered a poor talent choice so is rarely seen.