Murky vs Rehgar
It is a little embarrasing but Rhegar beats Murky. Rehgar's lighting shield will kill Murky and Rhegars wolf lunge takes most of Murky's health. You can lane against Rehgar but you have to back off when Rehgar uses his lightning shield. Also wait for Rhegar to use his lightning shield then place pufferfish down. Rehgar can still melee the pufferfish but it is a little harder for him to do so.
Late game Rehgar just gets stronger. Best bet is to go after an easier target in teamfights unless rhegar is low.