Murky vs Kharazim
Kharazim is a nightmare for Murky until you get Fish Tank. Kharazim can easily kill Murky's pufferfish and chase Murky down. Kharazim also has heals so Murky can not force him to retreat by kamikaze diving him.
Once Murky has Fish Tank the fight gets a little more fair. However Kharazim still has a slight advantage and has an escape. Getting Slippery When Wet will let you chase Kharazim down.