Murky vs Guldan
Guldan is impossible to lane against. He has a flame attack is on a low cool down and can kil your egg. He has good wave clear and can easily kill Murky. Guldan will not run out of mana or health so Murky can not force him to retreat. Best plan of action is to switch lanes.
If you go slime build at lvl 16 Murky can out damage Guldan's heal. When Guldan tries to leach life from you can bubble to prevent that.